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Histone methylations in the developing central nervous system and in neural tube defects
(De Gruyter, 2018-05)
Understanding central nervous system genesis is of crucial relevance to decode different human diseases such as microcephaly or neural tube defects, which arise from incorrect developmental processes. Epigenetic mechanisms ...
MicroRNAs and the neural crest: From induction to differentiation
(Elsevier Science, 2018-12)
MicroRNAs are small noncoding RNAs that can control gene expression by base pairing to partially complementary mRNAs. Regulation by microRNAs plays essential roles in diverse biological processes such as neural crest ...
Epigenetic regulation in neural crest development
(Academic Press Inc Elsevier Science, 2014-11)
The neural crest is a migratory and multipotent cell population that plays a crucial role in many aspects of embryonic development. In all vertebrate embryos, these cells emerge from the dorsal neural tube then migrate ...
Neural Differentiation of Transplanted Neural Stem Cells in a Rat Model of Striatal Lacunar Infarctin: Ligth Electron Microscopic Observations
(Frontiers MediaGrupo de Neurociencias de AntioquiaLausana, Suiza, 2023)
DNA methyltransferase 3B regulates duration of neural crest production via repression of Sox10
(National Academy of Sciences, 2014-11)
Neural crest stem cells arise within the central nervous system but then undergo an epithelial-to-mesenchymal transition to migrate away and contribute to the peripheral nervous system and craniofacial skeleton. Here we ...
Deep Learning Neural Networks Highly Predict Very Early Onset of Pluripotent Stem Cell Differentiation
(Cell Press, 2019-04-09)
Deep learning is a significant step forward for developing autonomous tasks. One of its branches, computer vision, allows image recognition with high accuracy thanks to the use of convolutional neural networks (CNNs). Our ...
GDNF/GFRα1 Complex Abrogates Self-Renewing Activity of Cortical Neural Precursors Inducing Their Differentiation
(Cell Press, 2018-03)
The balance between factors leading to proliferation and differentiation of cortical neural precursors (CNPs) determines the correct cortical development. In this work, we show that GDNF and its receptor GFRα1 are expressed ...
Dissociable Neural Information Dynamics of Perceptual Integration and Differentiation during Bistable Perception
(Oxford Univ Press Inc, 2020-03)
At any given moment, we experience a perceptual scene as a single whole and yet we may distinguish a variety of objects within it. This phenomenon instantiates two properties of conscious perception: integration and ...
Zero-shot Multi-Domain Dialog State Tracking Using Descriptive Rules
(Cornell University, 2020-09)
In this work, we present a framework for incorporating descriptive logical rules in state-of-the-art neural networks, enabling them to learn how to handle unseen labels without the introduction of any new training data. ...